Important notice

Meds75+ – information regarding the use for persons aged 75+

Substances A-Z
  • Da

  • Dalteparinum natricum
    Class C
    Suitable for older persons, with specific cautions. Severe renal insuffiency potentiates the response. A significant adverse effect is increased risk of bleeding.
  • De

  • Denosumabum
    Class C
    Suitable for older persons, with specific cautions. Insufficient intake of calcium in nutrition or hypocalcaemia must be corrected before the treatment and during it. The optimal duration of therapy is unknown. Remember the possibility of atypical femoral fractures and osteonecrosis of the jaw.
  • Desloratadinum
    Class A
    Suitable for older persons. Reduce the dose in severe renal insufficiency. Concurrent use with clopidogrel can increase desloratadine level. May cause fatigue.
    Class A
    Suitable for older persons. Reduce the dose in severe renal insufficiency. Concurrent use with clopidogrel can increase desloratadine level. May cause fatigue.
  • Desmopressini acetas
    Class D
    Avoid use in older persons. Risk of fluid retention and hyponatraemia. Initiation of therapy under specialist´s supervision is possible as treatment for ADH deficiency.
  • Dexamethasoni natrii phosphas
    Class C
    Suitable for older persons, with specific cautions. Avoid long-term use. Take adverse effects and interactions into account.
    Class A
    Suitable for older persons. For temporary use. Long term use only under supervision by an ophthalmologist. Do not use if fungal or viral infection is suspected.
  • Dexamethasonum
    Class C
    Suitable for older persons, with specific cautions. Avoid long-term use. Take adverse effects and interactions into account.
    Class A
    Suitable for older persons. For temporary use. Long term use only under supervision by an ophthalmologist. Do not use if fungal or viral infection is suspected.
  • Dexpanthenolum
  • Dextromethorphani hydrobromidum
    Class D
    Avoid use in older persons. Serotonergic. Take significant adverse effects into account. Take interactions into account especially with benzodiazepines and memantine.
    Class D
    Avoid use in older persons. Serotonergic. Significant adverse effects include tremor, palpitations, headache, nausea, constipation, tiredness, dizziness and risk for falls. Take interactions into account especially with memantine.
  • Di

  • Diazepamum
    Used as "PSYCHOLEPTICS"
    Class D
    Avoid use in older persons. Sedative. A long-acting. Significant adverse effects include drug addiction, cognitive disporder and risk for traffic accidents. Increases risk for falls. Paradoxically, may increase anxiety, restlessness and aggression. Avoid consuming grapefruit during treatment.
  • Diclofenacum diethylaminum
    Class A
    Suitable for older persons. Systemic absorption is low when applied on to the skin as specified in the instructions for use.
  • Diclofenacum kalicum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding.Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
  • Diclofenacum natricum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding. Note increased risk of gastrointestinal bleeding and cardiovascular events. Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding.Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
  • Digoxinum
    Used as "CARDIAC THERAPY"
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even mild renal insufficiency. Maximun daily dose for older persons: 0.125 mg. Maximum concentration for older persons: 1.0 nmol/l. Take interactions into account.
  • Diltiazemi hydrochloridum
    Class D
    Avoid use in older persons. Use only in special cases. Significant adverse effects include constipation, bradycardia and swelling. Take interactions into account, especially with digoxin and beta blockers. Avoid consuming grapefruit during treatment.
  • Do

  • Donepezili hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Risk of QT prolongation. May exacerbate an existing COPD. Predisposes to cardiac conduction disorders, such as bradycardia. Note adverse effects affecting the gastrointestinal tract. Take interactions into account. Anticholinergic drugs weakens the efficacy of anti-Alzheimer´s drugs.
  • Doxylamini hydrogenosuccinas
    Class D
    Avoid use in older persons. Strongly anticholinergic. Sedative. Increases risk for falls. Weakens the efficacy of anti-Alzheimer´s drugs.
  • Du

  • Duloxetini hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Serotonergic. Use must be started at small doses (30 mg) and discontinued gradually. Increases risk for falls. Take interactions into account.
  • Dutasteridum
    Used as "UROLOGICALS"
    Class A
    Suitable for older persons.
  • Dy

  • Dydrogesteronum
    Class D
    Avoid use in older persons. In systemic use, take adverse effects into account, such as risk of cardiovascular diseases and venous thromboembolisms. Take interactions into account.

Icon explanation

Class A A (green): Suitable for the older persons. The medicinal substance can be used as in younger patients. Changes due to aging do not affect the dose or frequency of administration, and the adverse reaction profile is not different from that of younger patients.

Class B B (grey): There is little research evidence, practical experience or efficacy in older persons.

Class C C (yellow): Suitable for older persons, with specific cautions. The medicinal substance can be used by older persons, but the dose might either have to be reduced, or the frequency of administration decreased due to mild or moderate renal insufficiency or a significant risk of interactions or adverse reactions.

Class D D (red): Avoid use in older persons. Use is possible only in exceptional cases or on a one-off basis. Changes due to aging predispose older persons to adverse or dangerous reactions to the drug. The risk of adverse reactions typically exceeds the benefits.

Meds75+ data source is Finnish Medicines Agency Fimea (licensed under CC BY 4.0).
Data updated on Mar 30, 2021.