Important notice

Meds75+ – information regarding the use for persons aged 75+

Substances A-Z
  • Ac

  • Aciclovirum
    Class C
    Suitable for older persons, with specific cautions. Applies to orally administered preparations. Reduce the dose and/or increase the dosing interval in severe renal insufficiency. May decrease renal function.
    Class A
    Topical treatment: Suitable for older persons.
    Class A
    Suitable for older persons. For temporary use in keratitis induced by herpes simplex.
  • Acidum acetylsalicylicum
    Used as "ANALGESICS"
    Class D
    Avoid use in older persons. Not suitable for pain treatment. Reduce the dose in moderate renal insufficiency. Do not use in severe renal insufficiency. Significant adverse effects include bleeding and damage of gastric mucosa. May reduce the effect of antihypertensives and drugs used for cardiac insufficiency. Increases the toxicity of methotrexate. Note acetylsalicylic acid in OTC drugs and combination products.
    Class C
    Suitable for older persons, with specific cautions. A significant adverse effect is increased risk of bleeding.
  • Acidum tranexamicum
    Class C
    Suitable for older persons, with specific cautions. Elimination is reduced in even mild renal insufficiency.
  • Acidum valproicum
    Used as "ANTIEPILEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Low albumin level in serum increases the response. Take into account adverse effects, such as hyponatraemia och changes in blood count. Monitor liver function.
  • Al

  • Alfuzosini hydrochloridum
    Used as "UROLOGICALS"
    Class C
    Suitable for older persons, with specific cautions. Significant adverse effects include orthostatic hypotension, dizziness and risk for falls. Avoid consuming grapefruit during treatment.
  • Allopurinolum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even mild renal insufficiency. Take interactions into account.
  • Ap

  • Apixabanum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in severe renal insufficiency. A significant adverse effect is increased risk of bleeding. Take interactions into account. Andexanet alfa can be used as an antidote.
  • Ar

  • Aripiprazolum
    Used as "PSYCHOLEPTICS"
    Class C
    Suitable for older perseons, with specific cautions. Significant adverse effects include cognitive disorder, confusion, extrapyramidal symptoms, orthostatic hypotension and risk of cardiovascular events. Increases risk for falls. Take several interactions into account. Non-pharmacological treatments are the first line approach in the management of behavioral and psychological symptoms of dementia. Weakens the efficacy of anti-Alzheimer´s drugs. Avoid consuming grapefruit during treatment.
  • At

  • Atenololum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even moderate renal insufficiency. Significant adverse effects include bradycardia and orthostatic hypotension. Take interactions into account, especially with drugs affecting the conduction pathways of the heart.
  • Be

  • Betamethasoni valeras
    Class C
    Topical treatment: Suitable for older persons, with specific cautions. Note adverse local effects and systemic absorption.
  • Betaxololi hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Start and continue therapy under supervision by an ophthalmologist. Remember systemic adverse effects. Take interactions into account.
  • Br

  • Brimonidini tartras
    Class C
    Suitable for older persons, with specific cautions. Start and continue therapy under supervision by an ophthalmologist.
  • Brinzolamidum
    Class C
    Suitable for older persons, with specific cautions. Start and continue therapy under supervision by an ophthalmologist. Avoid use in severe renal insufficiency.
    Class C
    Suitable for older persons, with specific cautions. Start and continue therapy under supervision by an ophthalmologist. Avoid use in case of renal insufficiency.
    Class C
    Suitable for older persons, with specific cautions. Start and continue therapy under supervision by an ophthalmologist. Avoid use in severe renal insufficiency.
  • Bu

  • Budesonidum
    Class C
    Suitable for older persons, with specific cautions. Adverse effects to glucocorticoids are emphasised in long-term use. Take interactions into account.
    Class A
    Suitable for older persons. Take into account possible systemic adverse effects. Take interactions into account.
  • Buprenorphini hydrochloridum
    Used as "ANALGESICS"
    Class C
    Suitable for older persons, with specific cautions. Opioid. Transdermal efficacy is weak in patients with cachexy. Dosage adjustment is usually not necessary in older persons. Start a laxative to prevent constipation.
  • Buprenorphinum
    Used as "ANALGESICS"
    Class C
    Suitable for older persons, with specific cautions. Opioid. Transdermal efficacy is weak in patients with cachexy. Dosage adjustment is usually not necessary in older persons. Start a laxative to prevent constipation.
  • Bupropioni hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Take into account the risk of convulsions and numerous interactions. Reduce the dose in even mild renal insufficiency. Increases risk for falls.
  • Buspironi hydrochloridum
    Used as "PSYCHOLEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even mild renal insufficiency. Avoid consuming grapefruit during treatment.
  • Ca

  • Calcitriolum
  • Candesartanum cilexetilum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even mild renal insufficiency. Monitor renal function during the pharmacotherapy. Avoid concurrent use of anti-inflammatory analgesics.
  • Carbamazepinum
    Used as "ANTIEPILEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Hyponatraemia is common adverse effect. Several other adverse effects, such as changes in blood count and risk of hepatic injury. Need for a Vitamin D supplement must be taken into account in long-term use. Take several and significant interactions into account before starting and discontinuing the use. Avoid consuming grapefruit during treatment.
  • Ce

  • Celecoxibum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding less than nonselective anti-inflammatory analgesics. Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
  • Cetirizini dihydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose and/or increase the dosing interval in even moderate renal insufficiency. May cause fatigue.
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose and/or increase the dosing interval in even moderate renal insufficiency. May cause fatigue.
  • Cl

  • Clarithromycinum
    Class D
    Avoid using in older persons. Reduce the dose in renal or hepatic insufficiency. Risk of QT prolongation. Take significant interactions into account.
  • Clioquinolum
  • Clopidogrelum
    Class C
    Suitable for older persons, with specific cautions. Prodrug. Genotype affects the activation. A significant adverse effect is increased risk of bleeding. Take interactions into account. Grapefruit reduces the response.
  • Da

  • Dalteparinum natricum
    Class C
    Suitable for older persons, with specific cautions. Severe renal insuffiency potentiates the response. A significant adverse effect is increased risk of bleeding.
  • De

  • Denosumabum
    Class C
    Suitable for older persons, with specific cautions. Insufficient intake of calcium in nutrition or hypocalcaemia must be corrected before the treatment and during it. The optimal duration of therapy is unknown. Remember the possibility of atypical femoral fractures and osteonecrosis of the jaw.
  • Dexamethasoni natrii phosphas
    Class C
    Suitable for older persons, with specific cautions. Avoid long-term use. Take adverse effects and interactions into account.
    Class A
    Suitable for older persons. For temporary use. Long term use only under supervision by an ophthalmologist. Do not use if fungal or viral infection is suspected.
  • Dexamethasonum
    Class C
    Suitable for older persons, with specific cautions. Avoid long-term use. Take adverse effects and interactions into account.
    Class A
    Suitable for older persons. For temporary use. Long term use only under supervision by an ophthalmologist. Do not use if fungal or viral infection is suspected.
  • Di

  • Diclofenacum kalicum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding.Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
  • Diclofenacum natricum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding. Note increased risk of gastrointestinal bleeding and cardiovascular events. Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding.Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
  • Digoxinum
    Used as "CARDIAC THERAPY"
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even mild renal insufficiency. Maximun daily dose for older persons: 0.125 mg. Maximum concentration for older persons: 1.0 nmol/l. Take interactions into account.
  • Do

  • Donepezili hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Risk of QT prolongation. May exacerbate an existing COPD. Predisposes to cardiac conduction disorders, such as bradycardia. Note adverse effects affecting the gastrointestinal tract. Take interactions into account. Anticholinergic drugs weakens the efficacy of anti-Alzheimer´s drugs.
  • Du

  • Duloxetini hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Serotonergic. Use must be started at small doses (30 mg) and discontinued gradually. Increases risk for falls. Take interactions into account.
  • Ec

  • Econazoli nitras
    Class C
    Topical treatment: Suitable for older persons, with specific cautions. In topical use, absorption takes place through broken skin. Take severe adverse effects into account, especially with warfarin.
  • Em

  • Empagliflozinum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose even in moderate renal insufficiency. Do not use in severe renal insufficiency. Consider the risk of dehydration and urinary tract infection.
  • En

  • Enalaprili maleas
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even moderate renal insufficiency. Monitor renal function during the pharmacotherapy. Avoid concurrent use of anti-inflammatory analgesics.
  • Enoxaparinum natricum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even moderate renal insufficiency. A significant adverse effect is increased risk of bleeding.
  • Et

  • Etoricoxibum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding less than nonselective anti-inflammatory analgesics.Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
  • Ex

  • Exenatidum
    Class C
    Suitable for older persons, with specific cautions. Limited practical experience of the long-acting preparation. Reduce the dose in moderate renal insufficiency. Do not use in severe renal insufficiency. Weight loss may occur.
  • Fa

  • Famotidinum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even moderate renal insufficiency. Older persons are at risk of adverse effects, such as dizziness and confusion.
  • Fe

  • Febuxostatum
    Class C
    Suitable for older persons, with specific cautions. Do not use on patients with severe cardiovascular diseases.
  • Fenofibratum
    Class C
    Suitable for older persons, with certain reservations. Reduce the dose in even mild renal insufficiency. Avoid use in severe renal insufficiency. Take interactions into account, especially with statins and warfarin.
  • Fentanylum
    Used as "ANALGESICS"
    Class C
    Suitable for older persons, with specific cautions. Opioid. Sedative. Serotonergic. Start pain management with orally administered opiod. Transdermal efficacy is weak in patients with cachexy. Start a laxative to prevent constipation. Nasal spray should be used only for breakthrough pain of cancer. Take significant interactions into account.
  • Fexofenadini hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose and/or increase the dosing interval in even moderate renal insufficiency. May cause fatigue. Take interactions into account.
  • Fl

  • Fluconazolum
    Class C
    Suitable for older persons, with specific cautions. Risk of QT prolongation. Reduce the dose in even moderate renal insufficiency. Monitor liver test values. Take several interactions into account, especially with warfarin.
  • Fludrocortisoni acetas
    Class C
    Suitable for older persons, with specific cautions. Note the strong mineralocorticoid effect on electrolytes. Off-label use for treatment of hypotension must be conducted with small doses and only after careful consideration.
  • Ga

  • Gabapentinum
    Used as "ANTIEPILEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Sedative. Reduce the dose in even mild renal insufficiency. Note especially central nervous system adverse effects. Take the interactions in the absorption phase into account.
  • Galantamini hydrobromidum
    Class C
    Suitable for older persons, with specific cautions. May exacerbate an existing COPD. Predisposes to cardiac conduction disorders, such as bradycardia. Note adverse effects affecting the gastrointestinal tract. Take interactions into account. Anticholinergic drugs weakens the efficacy of anti-Alzheimer´s drugs.
  • Hy

  • Hydrochlorothiazidum
    Used as "DIURETICS"
    Class C
    Suitable for older persons, with specific cautions. Efficacy is lost in renal insufficiency. Take into account the risk of orthostatic hypotension and hyponatraemia and -kalemia.
    Class C
    Suitable for older persons, with specific cautions. Efficacy is lost in renal insufficiency. Take into account the risk of orthostatic hypotension and hyponatraemia and -kalemia.
    Class A
    Suitable for older persons. Efficacy is reduced in renal insufficiency. Note possibility of orthostatic hypotension and electrolyte disturbances.
  • Hydrocortisoni acetas
    Class A
    Topical treatment: Suitable for older persons.
  • Hydromorphoni hydrochloridum
    Used as "ANALGESICS"
    Class C
    Suitable for older persons, with specific cautions. Opioid. Sedative. Reduce the dose in moderate renal insufficiency. Start a laxative to prevent constipation.
  • Hydroxychloroquini sulfas
    Used as "ANTIPROTOZOALS"
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even moderate renal insufficiency.
  • Ib

  • Ibuprofenum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding. Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding. Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
    Used as "ANALGESICS"
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding. Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
    Used as "ANALGESICS"
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. Note increased risk of gastrointestinal bleeding and cardiovascular events. Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
    Class A
    Suitable for older persons. Systemic absorption is low when applied on to the skin as specified in the instructions for use.
  • In

  • Indapamidum
    Used as "DIURETICS"
    Class C
    Suitable for older persons, with specific cautions. Efficacy is lost in renal insufficiency. Take into account the risk of orthostatic hypotension and hyponatraemia and -kalemia.
    Class C
    Suitable for older persons, with specific cautions. Efficacy is lost in renal insufficiency. Take into account the risk of orthostatic hypotension and hyponatraemia and -kalemia.
  • Ka

  • Kalii chloridum
    Class A
    Suitable for older persons.
  • Ke

  • Ketoprofenum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Use cautiously for persons with decreased renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding. Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
    Class A
    Suitable for older persons. Systemic absorption is low when applied on to the skin as specified in the instructions for use.
  • La

  • Lamotriginum
    Used as "ANTIEPILEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Several adverse effects. Take into account especially common and sometimes serious adverse skin reactions.
  • Le

  • Levetiracetamum
    Used as "ANTIEPILEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Sedative. Reduce the dose in even mild renal insufficiency. Note especially central nervous system adverse effects.
  • Levocetirizini dihydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose and/or increase the dosing interval in even moderate renal insufficiency. May cause fatigue.
  • Lo

  • Lorazepamum
    Used as "PSYCHOLEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Sedative. For short-term use only. Addictive. Significant adverse effects include cognitive disporder and risk for traffic accidents. Increases risk for falls. Paradoxically, may increase anxiety, restlessness and aggression. Non-pharmacological treatments are primary in the treatment of insomnia and behavioral symptoms.
  • Me

  • Meloxicamum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Reduce the dose in moderate and severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding.Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
  • Memantini hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in severe renal insufficiency. Take significant interactions into account with phenytoin, ketamine and dextromethorphan which is used as a cough medicine in self-care.
  • Metformini hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even mild renal insufficiency. Do not use in severe renal insufficiency or tissue hypoxia. May reduce the absorption of vitamin B12. Take into account risk of lactic acidosis. Cease is required in cases of gastroenteritis or dehydration, and before surgery or imaging with a contrast agent.
  • Methotrexatum
    Class C
    Suitable for older persons, with specific cautions. In other conditions than cancer treatment administration only once weekly. Organtoxic such as kidneys, liver and bone marrow. Remember monitoring safety tests. Reduce the dose in renal insufficiency. Avoid use in case of severe renal insufficiency. Take several interactions into account.
  • Methylprednisoloni acetas
    Class C
    Suitable for older persons, with specific cautions. Adverse effects are emphasised in long-term use. Take interactions into account.
  • Methylprednisolonum
    Class C
    Suitable for older persons, with specific cautions. Adverse effects are emphasised in long-term use. Take interactions into account.
  • Metronidazolum
    Class C
    Topical treatment: Suitable for older persons, with specific cautions. In topical use, absorption takes place through mucous membranes and broken ski. Take interactions into account, especially with warfarin. Do not drink alcohol during treatment.
    Class C
    Suitable for older persons, with specific cautions. In topical use, absorption takes place through mucous membranes and broken skin. Take interactions into account, especially with warfarin. Do not drink alcohol during treatment.
    Used as "ANTIPROTOZOALS"
    Class C
    Suitable for older persons, with specific cautions. Take interactions into account, especially with warfarin. May cause dysgeusia and dark-coloured urine. Avoid alcohol during treatment and one day after thereafter.
  • Mi

  • Miconazoli nitras
    Class C
    Topical treatment: Suitable for older persons, with specific cautions. In topical use, absorption takes place through broken skin. Take severe adverse effects into account, especially with warfarin.
    Class C
    Topical treatment: Suitable for older persons, with specific cautions. In topical use, absorption takes place through mucous membranes and broken ski. Take interactions into account, especially with warfarin. Alternative: nystatin.
  • Mirtazapinum
    Class C
    Suitable for older persons, with specific cautions. Slightly anticholinergic. Sedative. Slightly serotonergic. Suitable in small doses for treating insomnia. Reduce the dose in even moderate renal insufficiency. Increases risk for falls.
  • Mo

  • Morphini hydrochloridum
    Used as "ANALGESICS"
    Class C
    Suitable for older persons, with specific cautions. Opioid. Sedative. Reduce the initial dose in renal insufficiency. Avoid use in severe renal insufficiency. Start a laxative to prevent constipation.
  • Na

  • Nabumetonum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Reduce the dose in moderate and severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding. Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
  • Naproxenum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding.Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding. Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
  • Naproxenum natricum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only. May decrease renal function. Avoid use in severe renal insufficiency. May increase blood pressure, worsen cardiac insuffiency and cause cardiovascular events. Increases risk of gastrointestinal bleeding.Take interactions into account, especially with anticoagulants. Remember that anti-inflammatory analgesics are commonly used in self-care.
  • Natrii alendronas trihydricus
    Class C
    Suitable for older persons, with specific cautions. Inappropriate for bedpatients. Do not use in severe renal insufficiency. The patient must be able to take the medicine with sufficient liquid and remain in an upright position for 30 minutes after ingestion. Recommended period of use: 5 years. Iron, magnesium, aluminium and calcium decrease absorption. Supervision by dentist recommended before starting therapy.
  • Natrii laurilsulfoacetas
    Class C
    Suitable for older persons, with specific cautions. For temporary use.
  • Natrii valproas
    Used as "ANTIEPILEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Low albumin level in serum increases the response. Take into account adverse effects, such as hyponatraemia och changes in blood count. Monitor liver function.
  • Ol

  • Olanzapinum
    Used as "PSYCHOLEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Anticholinergic. Sedative. Regularly assess the need for pharmacotherapy. Significant adverse effects include cognitive disorder, confusion, extrapyramidal symptoms, orthostatic hypotension and risk of cardiovascular events. Increases risk for falls. Non-pharmacological treatments are the first line approach in the management of behavioral and psychological symptoms of dementia.
  • On

  • Ondansetronum
    Class C
    Suitable for older persons, with specific cautions. May prolong the QT interval.
  • Ox

  • Oxazepamum
    Used as "PSYCHOLEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Sedative. For short-term use only. Addictive. Significant adverse effects include cognitive disporder and risk for traffic accidents. Increases risk for falls. Paradoxically, may increase anxiety, restlessness and aggression. Non-pharmacological treatments are primary in the treatment of insomnia and behavioral symptoms.
  • Oxcarbazepinum
    Used as "ANTIEPILEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in severe renal insufficiency. Several adverse effects, such as hyponatraemia, changes in blood count and risk of hepatic injury. Need for a Vitamin D supplement must be taken into account in long-term use.
  • Oxycodoni hydrochloridum
    Used as "ANALGESICS"
    Class C
    Suitable for older persons, with specific cautions. Opioid. Sedative. Risk of QT prolongation. Reduce the dose in even mild renal insufficiency. Start a laxative to prevent constipation. Take interactions into account. Avoid consuming grapefruit during treatment.
  • Pi

  • Pilocarpini hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Start and continue therapy under supervision by an ophthalmologist.
  • Pr

  • Pramipexolum
    Class C
    Suitable for older persons, with specific cautions. Sedative. Start therapy under specialist supervision. Reduce the dose in even moderate renal insufficiency. The most common adverse effects are orthostatic hypotension, gastrointestinal symptoms, drowsiness, hallucinations, confusion and sudden bouts of falling asleep. Take interactions into account, especially with antipsychotics.
  • Prednisolonum
    Class C
    Suitable for older persons, with specific cautions. Adverse effects are emphasised in long-term use. Take interactions into account.
  • Pregabalinum
    Used as "ANTIEPILEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Sedative. Reduce the dose in even mild renal insufficiency. May prolong the QTc interval. Note especially central nervous system adverse effects. Addiction might develop.
  • Propranololi hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Non-selective beta blocker. Significant adverse effects include sleep disorders, depression, muscular weakness and bronchial contraction. Take interactions into account, especially with drugs affecting the conduction pathways of the heart.
  • Ps

  • Pseudoephedrini hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. For short-term use only (<10 days) as necessary. Increase the dosing interval in even mild renal insufficiency. Take into account sympathomimetic effects.
  • Ra

  • Ramiprilum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even moderate renal insufficiency. Monitor renal function during the pharmacotherapy. Avoid concurrent use of anti-inflammatory analgesics.
  • Ri

  • Risperidonum
    Used as "PSYCHOLEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Regularly assess the need for pharmacotherapy. Reduce the dose in even mild renal insufficiency. Significant adverse effects include cognitive disorder, confusion, extrapyramidal symptoms, orthostatic hypotension and risk of cardiovascular events. Increases risk for falls. Non-pharmacological treatments are the first line approach in the management of behavioral and psychological symptoms of dementia.
  • Rivaroxabanum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even moderate renal insufficiency. A significant adverse effect is increased risk of bleeding. Take interactions into account. Andexanet alfa can be used as an antidote.
  • Rivastigminum
    Class C
    Suitable for older persons, with specific cautions. May exacerbate an existing COPD. Predisposes to cardiac conduction disorders, such as bradycardia. Note adverse effects affecting the gastrointestinal tract. Take interactions into account. Anticholinergic drugs weakens the efficacy of anti-Alzheimer´s drugs.
  • Sa

  • Saccharomyces boulardii
    Class C
    Suitable for older persons, with specific cautions. Medicine is destroyed when used in combination with antifungal agents. Do not use for patients with impaired immune system.
  • Sacubitrilum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even moderate renal insufficiency. Do not use in combination with an ACE inhibitor.
  • Saxagliptinum
    Class C
    Suitable for older persons, with specific cautions. Limited clinical experience of use in older persons. Not suitable for patients with hepatic insufficiency. Reduce the dose even in moderate renal insufficiency. Note danger of peripheral fluid retention.
  • Se

  • Selegilini hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Serotonergic. Reduce the dose in even mild renal insufficiency. Significant adverse effects include orthostatic hypotension, hallucinations, confusion, dyskinesia, headache, dizziness and bradycardia. Do not use together with other serotonergic preparations.
  • Sertralini hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Serotonergic. Significant adverse effects include hyponatraemia and increased risk of bleeding. Increases risk for falls. Take interactions into account. Avoid consuming grapefruit during treatment.
  • Si

  • Simvastatinum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in severe renal insufficiency. Possible adverse effects include muscle pain and muscular weakness. Take interactions into account. Avoid consuming grapefruit during treatment.
  • Sp

  • Spironolactonum
    Used as "DIURETICS"
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in moderate renal insufficiency. Do not use in severe renal insufficiency. Note risk of hyperkalaemia.
  • Su

  • Sulpiridum
    Used as "PSYCHOLEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Risk of QT prolongation. Regularly assess the need for pharmacotherapy. Reduce the dose in even mild renal insufficiency. Significant adverse effects include cognitive disorder, confusion, extrapyramidal symptoms, orthostatic hypotension and risk of cardiovascular events. Increases risk for falls. Non-pharmacological treatments are the first line approach in the management of behavioral and psychological symptoms of dementia.
  • Ta

  • Tadalafilum
    Used as "UROLOGICALS"
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even mild renal insufficiency. Reduce the dose in even mild hepatic insufficiency. Significant adverse reactions include hypotension, ortostatic hypotension, headache and visual disturbances. Take several interactions into account, especially with nitrates and alpha-blocking agents. Avoid consuming grapefruit during treatment.
  • Tamsulosini hydrochloridum
    Used as "UROLOGICALS"
    Class C
    Suitable for older persons, with specific cautions. Significant adverse effects include orthostatic hypotension, dizziness and risk for falls.
  • Te

  • Terbinafini hydrochloridum
    Class C
    Suitable for older persons, with specific cautions. Reduce the dose in even moderate renal insufficiency. Contraindication: severe hepatic insufficiency. Take significant interactions into account.
    Class A
    Topical treatment: Suitable for older persons. Systemic absorption is low when applied on to the skin as specified in the instructions for use.
  • Ti

  • Ticagrelorum
    Class C
    Suitable for older persons, with specific cautions. A significant adverse effect is increased risk of bleeding. Take several interactions into account. Avoid consuming grapefruit juice during treatment.
  • Timololi maleas
    Class C
    Suitable for older persons, with specific cautions. Start and continue therapy under supervision by an ophthalmologist. Remember systemic adverse effects. Take interactions into account.
  • Tr

  • Trimethoprimum
    Class C
    Suitable for older persons. Reduce the dose in severe renal insufficiency. Contraindicated in case of severe hepatic insufficiency. Take into account the risks when used in combination with anti-inflammatory analgesics, AT1-blockers/ACE-inhibitors, spironolactone and clozapine.
  • Vi

  • Vildagliptinum
    Class C
    Suitable for older persons, with specific cautions. Not suitable for patients with hepatic insufficiency. Reduce the dose in even moderate renal insufficiency.
  • Wa

  • Warfarinum natricum
    Class C
    Suitable for older persons, with specific cautions. A significant adverse effect is increased risk of bleeding. Interactions common, note especially anti-inflammatory analgesics, SSRIs, OTC medicines and natural remedies.
  • Zo

  • Zopiclonum
    Used as "PSYCHOLEPTICS"
    Class C
    Suitable for older persons, with specific cautions. Sedative. For short-term use only. Significant adverse effects include drug addiction, cognitive disporder and risk for traffic accidents. Increases risk for falls. May cause metallic taste in the mouth. Paradoxically, may increase anxiety, restlessness and aggression. Non-pharmacological treatments are primary in the treatment of insomnia.

Icon explanation

Class A A (green): Suitable for the older persons. The medicinal substance can be used as in younger patients. Changes due to aging do not affect the dose or frequency of administration, and the adverse reaction profile is not different from that of younger patients.

Class B B (grey): There is little research evidence, practical experience or efficacy in older persons.

Class C C (yellow): Suitable for older persons, with specific cautions. The medicinal substance can be used by older persons, but the dose might either have to be reduced, or the frequency of administration decreased due to mild or moderate renal insufficiency or a significant risk of interactions or adverse reactions.

Class D D (red): Avoid use in older persons. Use is possible only in exceptional cases or on a one-off basis. Changes due to aging predispose older persons to adverse or dangerous reactions to the drug. The risk of adverse reactions typically exceeds the benefits.

Meds75+ data source is Finnish Medicines Agency Fimea (licensed under CC BY 4.0).
Data updated on Mar 30, 2021.