Ibuprofenum, Codeini phosphas hemihydricus

Medicinal product name Brufen Plus 400 mg/30 mg film-coated tablets
Pharmaceutical form Film-coated tablet
Strength 400 mg/30 mg 
Information from the MAH on shortages Not available
predicted availability date: not notified
Legal status Rx Prescription (Pr.)
Package leafletPDF 25-07-2023
Summary of product characteristicsPDF 25-07-2023
Risk minimisation measuresVēstule veselības aprūpes speciālistam Vēstule veselības aprūpes speciālistam
ATC code N02AJ08 Analgesics
Information for Marketing authorisation holdersView

Important notice

Additional information regarding the use for persons aged 75+

If used as "ANALGESICS"
SubstanceClassComment
IbuprofenumCSuitable for older adults, with specific precautions. For short-term use only. Do not use in severe renal impairment. Increases swelling, worsens renal and heart failure and cause cardiovascular events. Increases risk of bleeding, especially in gastrointestinal tract. Consider potential interactions, especially with preparations that increase risk of bleeding.
Codeini phosphas hemihydricusDAvoid use in older adults. Sedative. Prodrug. Genotype affects the response. Increases the risk of confusion and falling. Start a laxative to prevent constipation. Consider potential interactions.

Medicinal products (1)

Availability of medicinal product Wholesalers Package size, content Primary packaging Maximum admissible pharmacy price (€ incl. VAT) Product No. Labelling
 Not available (according to the information provided by wholesalers)
predicted availability date: not notified
currently no information on availability from any wholesaler N30
(400 mg/30 mg)
Al/PVDC//PVC/PVDC blister    14-0009-01 Labelling text Labelling text Aug 18, 2022

Registration information

Marketing authorisation No. 14-0009
Date of authorisation Jan 20, 2014
Marketing authorisation holder, country Viatris Healthcare Limited, Ireland